A clean room is designed to have a controlled level (concentration) of suspended particles in the air. For that purpose what is required are special building materials (ceilings, floors and walls / partitions), suitable assembly and specialized ventilation / air conditioning that supply the required large amounts of air through high retention filters (HEPA) for the removal and / or attenuation of existing particles.

The management of hazardous or explosive materials and activities that emit gases and fumes take place in medical and chemical laboratories. These activities are carried out under fume hoods in medical laboratories. Laboratory fume cupboards operate under negative pressure, they do not allow the escape of gases and define enclosed spaces to protect personnel.

Modern surgery sets strict standards for the quality of air in operating theatres. These spaces must be kept clean and free of particles.

The good condition of an air-conditioning system in terms of hygiene is a key element in maintaining at a high level the quality of indoor air. In this way an important factor in human health is ensured.